Background: The prognosis of several malignancies is associated with blood groups ABOs, however, the mechanisms still remain unknown. The study was designed to explore the possible association among the esophageal cancer, as well as stomach, colon, rectum and liver cancer with blood groups ABO and Rh factors in Bangladeshi populations. Methods: The data of age, gender, ABO and Rh blood group type of cancer patients were collected from Chittagong medical college and from different oncologist chamber. The study sample consisted of 88 liver cancer,178 stomach cancer,125 colon cancer,45 rectum cancer,109 esophagus cancer and 1024 healthy male and female controls were assessed for the association with ABO blood groups. For statistical analysis, Chi-square test was used to assess the relationship between ABO blood groups and oral cancer, where the probability level was fixed at ≤0.05.
Results: High incidence of stomach, rectum and liver cancer patients is associated with blood type A and colon cancer associated with blood type B compared with control group; where the calculated value of χ2 is greater than the table value with df (degrees of freedom) 1 at 5% level of significance, p<0.05.
Conclusion: Patients with the blood group A and B were more likely to develop gastric and liver cancer. In this regard more studies are necessary to illuminate the role of ABH antigens in the progression of gastric and liver cancers.
ABO Blood Type and Threat of GIT Cancer and Liver Cancer In Bangladeshi Populations
- S. M. Zahid Hosen
- Sajjad Mohammed Yusuff
- Sabuj Barua
- Ayesha Chowdhury
- Mohammad Arifuzzaman
S. M. Zahid Hosen
Molecular Modeling and Drug Design Laboratory, Pharmacology Research Division, Bangladesh Council of Scientific a nd Industrial Research, Chittagong-4220, Bangladesh
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Sajjad Mohammed Yusuff
Department of Radiotherapy, Chittagong Medical College & Hospital, Chittagong
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Sabuj Barua
Department of Pharmacy, Southern University Bangladesh, Chittagong
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Ayesha Chowdhury
Department of Pharmacy, University of Science & Technology Chittagong, Chittagong-4202, Bangladesh
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Mohammad Arifuzzaman
Department of Natural Sciences, LAGCC, City University of New York (CUNY), New York( Corresponding Author)
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Cite this:
Zahid Hosen, S. M., Yusuff, S. M., Barua, S., Chowdhury, A., & Arifuzzaman, M. (2018). ABO Blood Type and Threat of GIT Cancer and Liver Cancer In Bangladeshi Populations. Journal of Medical Biomedical and Applied Sciences, 6(4), 36–39. https://doi.org/10.15520/jmbas.v6i4.105
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