Objective: Our aim in this study is to determine the possibility that patients with IUGR (intrauterine growth retardation)
will be able to look at the adenonetin levels in the early stages of pregnancy and to have IUGR. In this respect, early
diagnosis, treatment and follow-up are aimed to reduce morbidity and mortality due to IUGR
Material Method: The study was carried out between January and March 2010. Zekai Tahir Burak Women’s Health
Education and Research Hospital 28-40. with 89 patients aged 18-40 years. Groups 44 IUGR patients and 45 normal
pregnant patients were divided into two groups. To examine the serum adiponectin level, an average of 3 cc was taken
in the gel biochemistry tubes and then centrifuged at 4000 10 minutes. The resulting serum samples were collected
for the ELISA kit and kept at -80 C until the day the patients were collected. In the study, adiponectin levels were
measured by serum ELISA (enzyme linked immunosorbent assay) method.
Results: In adiponectin evaluation, mean value was 105.90 19.02 pg / ml for the IUGR group, 65.96 16.5 pg / ml
for the control group and 1.6 times higher for the IUGR group( p < 0.001)
Conclusion: In this study, the increased adiponectin levels of IUGR patients were significantly higher than those of
IUGR patients, suggesting that pregnancies of IUGR patients can be measured high in the first weeks and if IUGR is
high in those weeks, IUGR can be predicted.
Importance of Serum Adiponectin Levels in The Prediction And Ethiopathogenesis of Intrauterine Growth Restriction
- Pervin Karlı
- Alper Başbuğ
- Çiğdem Kılıç
- Gülşen Kutluer
- İshak Artar
- Hacer Cavidan Gülerman
Pervin Karlı
Department of Obstetrics and Gynecology, Amasya University Research Hospital, Amasya, Turkey
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Alper Başbuğ
Department of Obstetrics and Gynecology, D¨uzce University Faculty of Medicine, Duzce, Turkey
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Çiğdem Kılıç
Dr. Zekai Tahir Burak Women’s Health Research and Education Hospital, Ankara, Turkey
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Gülşen Kutluer
Dr. Zekai Tahir Burak Women’s Health Research and Education Hospital, Ankara, Turkey
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İshak Artar
Dr. Zekai Tahir Burak Women’s Health Research and Education Hospital, Ankara, Turkey
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Hacer Cavidan Gülerman
Dr. Zekai Tahir Burak Women’s Health Research and Education Hospital, Ankara, Turkey
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Cite this:
Karlı, P., Başbuğ, A., Kılıç, Çiğdem, Kutluer, G., Artar, İshak, & Gülerman, H. C. (2018). Importance of Serum Adiponectin Levels in The Prediction And Ethiopathogenesis of Intrauterine Growth Restriction. Journal of Medical Biomedical and Applied Sciences, 6(6), 73–77. https://doi.org/10.15520/jmbas.v6i6.122
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