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Anti-inflammatory Effect of Pequi Oil (Caryocar brasiliense) in Acute Respiratory Distress Syndrome

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Sousa, T. C. de. (2016). Anti-inflammatory Effect of Pequi Oil (Caryocar brasiliense) in Acute Respiratory Distress Syndrome. Journal of Medical Biomedical and Applied Sciences, 1. https://doi.org/10.15520/.v1i0.2
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Abstract

Introduction: Acute lung lesion (ALL) and the more severe form, acute respiratory distress syndrome (ARDS), are the common denominator of many diseases that can cause exaggerated lung inflammation Objectives: The aim of this study was to analyze the anti-inflammatory action of pequi oil (Caryocar brasiliense) in an experimental model of acute lung inflammation induced in mice. Methods: Fifteen male Rattus novergicus were divided into three groups: falsely operated (abdominal incision), sham (ischemia and intestinal reperfusion – I/R-1 without treatment); treated (I/R + pequi essential oil).  Results: The treated group had less inflammatory cells, when compared with the sham group (p<0.001). Moreover, the results suggest that the treated group did not significantly differ from the falsely operated group. Conclusion: It is suggested that nebulized pequi oil reduces the pulmonary inflammatory response to injury resulting from the I/R-i lesion.
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