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Benign leiomyoma metastasizing to multiple organs and literature review

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Gagliardi c, P. A. wright A. (2017). Benign leiomyoma metastasizing to multiple organs and literature review. Journal of Medical Biomedical and Applied Sciences, 3(12). https://doi.org/10.15520/.v3i12.27
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Abstract

Uterine leiomyomas are highly common. Their incidence is generally cited as 20-25%, but has been  shown to be as high as 70-80% in studies using histologic or sonographic examination. Distant metastasis is extremely rare and is of unknown etiology. It primarily affects women of reproductive age and  might appear years after gynecological procedures such as myomectomy or hysterectomy.

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References

  1. Sreiner PE (1939) Metastasizing fibroleiomyoma of the uterus. AM J Patho; 15: 89-109 .
  2. Beck MM, Biswas B, Dsouza A et al. (2012) Benign metastasizing leiomyoma after hysterectomy and bilateral salpingo-oophorectomy. Hong Kong medical journal 18: 153-155.
  3. Bowen JM, Cates JM, Kash S (2012) Genomic imbalances in benign metastasizing leiomyoma: characterization by conventional karyotypic, flurescence in situ hybridization, and whole genoma SNP array analis. Cancer Genetics 205: 249-254.
  4. Abramson S, Glikson RC, Goldstein JD et al. (2001) benign metastasizing leiomyomas: clinical, imaging and pathological correlation. AJR Am J Roentgenol; 176: 1409-1413.
  5. Pitts S, Oberstein EM, Glassberg MK (2004) benign metastasizing Leiomyoma and Lymphangiomatosis: Sex- specific disease? Cli Chest Med, 25: 343-360.
  6. Wentling GK, Sevin BU, Geiger XJ, et al. (2005) Benign metastasizing Leiomyoma responsive to megestrol: case report and review of literature. Int J Gynecol cancer; 15: 1213-1217.
  7. Nasu K, Tsuno A, Takai N, et al. (2008) a case of benign metastasizing Leiomyoma treated by surgical castration, followed by aromatase inhibitor, anastrozole. Arch Gynecol Obstet.

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