You have access

Bleeding feature in the Hematology department in Brazzaville, Congo

Cite this:
Felix Malanda, Irene Ondzoto Ibata, Alexis Elira Dokekias, L. O. N. J. D. O. G. O. (2017). Bleeding feature in the Hematology department in Brazzaville, Congo. Journal of Medical Biomedical and Applied Sciences, 5(9). https://doi.org/10.15520/.v5i9.77
Copyright @ 2022 Interactive Protocols
Article Views
175
Altmetric
1
Citations
-

Abstract

Background: Epidemiological and clinical characteristics data of patients with bleeding symptoms are unknown.

Methods: a total of 6961 medical records of patients admitted in the hematology department in a teaching hospital from 2000 to 2016 were reviewed. We enrolled in the study all patients’ medical records that were reporting bleeding complications and analyzed retrospectively their epidemiological data, severity, clinical and biological characteristics.

Results: A total of 35 people (20 men and 15 women), with a median age of 29 (range 3 and 76) years had bleeding complications. The overall incidence of bleeding complication in the hematology department was 0.56%. The bleeding was significantly minor (51.23%). Among this group, petechiae was the most common hemorrhage symptoms: 31.71%.The bleeding was major in 48.77%. In this group, the principal cause of the bleeding events was acute leukemia (n=13; 37.41%); that was the main likely cause of intracranial hemorrhage which accounted for 29.27%. Hemophilia was the second cause of bleeding episode (n=5; 14.29%) followed by bone marrow failure (n=4; 11.43%). The median platelet count was 39.92 (range 10 and 253) G/L.

Conclusion: Bleeding event is rare and mostly associated with acute leukemia. The high proportion of intracranial hemorrhage in this group of pathology requests further studies on the outcome and predictive factors of it.

Key words: bleeding complications, epidemiology, clinical characteristics, Congo

 Additional Information

Descargas

Los datos de descargas todavía no están disponibles.

##plugins.generic.articleMetricsGraph.articlePageHeading##

Content

Section

Citas

  1. . S. Schulman, C. Kearon. Definition of major bleeding in clinical investigations of antihemostatic medical products in non-surgical patients.JTH. 3(4)(2005) 692-694.
  2. . C.C.Callow, R. Swindell, W. Randall, R. Chopra. The frequency of bleeding complications in patients with hematological malignancy following the introduction of a stringent prophylactic platelet transfusion policy.BJH. 118(2002) 677-682.
  3. . L.O. Ngolet, J.D. Okouango Guelongo Ova, Elira Dokekias A. Les hémopathies lymphoides chroniques. Annales de L’UMNG. 16(2016) ; 1-7.
  4. .C.Y.Chen, C.H.Tai, A.Cheng, H.C.WU, W.Tsay, J.H.Liu, P.Y.Chen, S.Y.Huang, J.L.Tang, H.F.Tien. Intracranial hemorrhage in adults patients with hematological malignancies. BMC. Medicine. 10.97(2012)2-9.
  5. .C.Y.Chen, CH.Thai, W.Tsay, P.Y.Chen, H.F.Tien. Prediction of fatal intracranial hemorrhage in patients with acute myeloid leukemia. Ann Oncol. 20(2009)1100-1104.
  6. .F.R.Rickles, A. Falanges, P.Montesinos, M.A.Sanz, B.Brenner, T. Barbui. Bleeding and thrombosis in acute leukemia : what does the future of therapy look like? Throm Res.120(suppl2)(2007)599-106.
  7. .J.Glass. Neurologic complications of lymphoma and leukemia. Semin Oncol. 33(2006) 342-347.
  8. . G. Claude. Hemophilia today. Kinesither Rev. 88(2009): 32-36.
  9. . F.Boehlena, P.Raddatz Mullera, B.Brandc. Hemophilie dans la pratique du médecin de famille. Frum Med Suiss. 11(2011): 452-457.
  10. . M.Seck , A. Sagna, M.S.Guéye, B.F.Faye, D.Sy, S.A. Touré, A Sall,A.O. Touré and S.Diop. Circumcision in hemophilia using low quantity of factor concentrates: experience from Dakar, Sénégal. BMC Hematology. 17(2017):1-6.
  11. .O. Badulescu, M. Badescu, M.Ciocoiu, F.Dudu. Immune thrombocytopenic purpura: correlation between thrombocytopenia severity and its clinical symptoms. Archives of Balkan Medical Union. 52(2017): 9-14.

Source

Indexing and Abstracting

  • 1
  • 2
  • 3
  • 4
  • 5
Google Scholar Url for the Journal is not available